Fig. 2.

Relative klotho mRNA expression from EBV-transformed lymphoblastoid cell lines from 60 unrelated Yoruba people of Ibadan, Nigeria from HapMap, segregated by genotype. Data for the three SNPs are shown, rs526906 (P = 0.003) (a), rs525014 (P = 0.022) (b) and rs571118 (P = 0.075) (c), comparing individuals homozygous for the protective allele to individuals with all other genotypes. Expression data were normalized using Illumina BeadStudio (Illumina Inc, San Diego, CA, USA) output as described in [18].