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. Author manuscript; available in PMC: 2010 Oct 4.
Published in final edited form as: J Allergy Clin Immunol. 2009 Jul 25;124(3):436–444e8. doi: 10.1016/j.jaci.2009.05.041

Table 3.

Treatment perceptions

Treatment Groups
Montelukast Placebo P-values*

Enhanced Neutral Enhanced Neutral Message
Effect
Drug
Effect
Interaction
Drug x Message
N 119 116 115 117
Statement Mean value at baseline (standard deviation)
Mean change from baseline (95% Confidence Interval)
Singulair (Montelukast) is an effective drug in
helping control asthma.
6.2 (1.7)
0.9 (0.5, 1.3)
6.3 (1.6)
0.5 (0.2., 0.8)
6.3 (1.6)
0.9 (0.6, 1.2)
6.4 (1.6)
0.2 (−0.1, 0.5)
0.001 0.35 0.47

If I were to take Singulair (Montelukast), it would
help my asthma
6.2 (1.7)
1.0 (0.7, 1.4)
6.2 (1.5)
0.5 (0.2, 0.8)
6.2 (1.5)
0.7 (0.4, 1.0)
6.3 (1.4)
0.0 (−0.3, 0.2)
<0.001 0.01 0.40

Singulair (Montelukast) is a weak drug for asthma. 4.0 (1.5)
−0.7 (−1.1, −0.4)
4.1 (1.6)
−0.5 (−0.8, −0.2))
4.0 (1.4)
−0.7 (−1, −0.4)
4.1 (1.7)
−0.3 (−0.6, 0.0)
0.04 0.56 0.73

Singulair (Montelukast) is likely to help people with
asthma
6.6 (1.6)
0.7 (0.4, 1.1)
6.8 (1.4)
0.2 (0.0, 0.5)
6.6 (1.4)
0.6 (0.4, 0.9)
6.6 (1.4)
0.2 (0.0, 0.5)
0.001 0.73 0.71
*

P-values presented are adjusted for clinic. Message effect = Effect of enhanced message independent of drug. Drug Effect = Effect of montelukast independent of message type. The interaction P-value evaluates for whether the drug effect is modified by the message effect

Baseline mean and difference from baseline are based on ordinal scale score of 1 to 9, strongly disagree to strongly agree, 5 is neutral.