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. Author manuscript; available in PMC: 2011 Oct 10.
Published in final edited form as: Eur J Pharmacol. 2010 Jun 30;644(1-3):10–16. doi: 10.1016/j.ejphar.2010.06.023

Fig. 4. Concentration-response curves of P2Y12 receptors with mutated residues in TM3 (F104S) and TM7 (S288P) in antagonist analysis.

Fig. 4

Cells were treated with 10μM ADP in the absence or the presence of (0.001-1 μM) AR-C69931MX. Data were normalized to the response in the presence of 20μM forskolin alone taken as 100%. (mean ± S.E.M., n=3).