Table 1.
E. coli proteins that interact with the β clamp via the β-binding pentapeptide motif QL[SD]LF or similar sequence [67].
β-interacting proteins | β-binding sequence | References |
---|---|---|
UmuD | 14TFPLF18 | [52, 53](1) |
DNA Pol V (UmuC) | 357QLNLF361 | [127, 128] |
DNA Pol IV (DinB) | 346QLVLGL351 | [68, 127, 129] |
DNA Pol II (Pol B) | 779QLGLF783 | [127] |
DNA Pol III (α-subunit) | 920QADMF924 | [130] |
δ-subunit Clamp Loader | 70AMSLF74 | [131] |
MutS | 812QMSLL816 | [132] |
Hda | 6QLSLPL11 | [133] |
(1)Although these residues reside in an important region for interactions with the β clamp, their identity is not required for UmuD to interact with β (see text Section 5).