Figure 2.

Release profiles of mitoxantrone from MTX-SL and LHRH-MTX-SL in phosphate-buffered saline A or isotonic glucose containing 10% human plasma B Release of mitoxantrone from different liposome preparations was evaluated by a dialysis method, followed by high-performance liquid chromatography analysis for determination of mitoxantrone. Results are expressed as means ± standard error of measurement of three independent measurements.

Abbreviations: LHRH, luteinizing hormone-releasing hormone; MTX, mitoxanthrone; SL, loaded liposomes.