Table. FCRs of [3H]CEt- and [125I]TCB-Labeled Protein From Human HDL3 by Lipase Knockout Mice.
Strain | [3H]CEt FCR (d−1) |
[125I]TCB FCR (d−1) |
CEt Selective Uptake ([3H]CEt FCR–[125I]TCB FCR) |
---|---|---|---|
WT (C57BL/6) | 5.36±0.22 | 1.87±0.23 | 3.49±0.32 |
HL-ko | 5.07±0.28 | 1.41 ±0.09* | 3.66±0.25 |
EL-ko | 4.29±0.36‡ | 1.35±0.34† | 2.94±0.25* |
HL/EL-dko | 4.47±0.13‡ | 1.54±0.21 | 2.93±0.34* |
FCRs for CEt and TCB were calculated as described in Methods (n=6 for each group).
P<0.05,
P<0.01,
P<0.001 vs WT.