. Author manuscript; available in PMC: 2010 Oct 4.

Published in final edited form as: Pharmacogenomics J. 2009 Jan 27;9(2):127–136. doi: 10.1038/tpj.2008.19

Table 1.

Coding region variants of hMATE1 (SLC47A1) identified in ethnically diverse populations

dbSNP ID numbers	CDS Position	Nucleotide Change	Amino Acid Position	Amino Acid Change	EC/EU	Allele Frequency
dbSNP ID numbers	CDS Position	Nucleotide Change	Amino Acid Position	Amino Acid Change	EC/EU	AA (n=136)	EA (n=136)	AS (n=136)	ME (n=136)
rs61733934	87	C→T	29	S→S	EU	0	0.022	0	0.007
NA	191	G→A	64	G→D	EC	0	0	0.007	0
rs34012597	270	C→T	90	F→F	EU	0.051	0	0	0
NA	373	C→T	125	L→F	EC	0	0	0.007	0.051
rs16960203	708	C→T	236	L→L	EC	0.007	0	0.083	0.076
NA	891	C→T	297	I→I	EC	0.008	0	0	0
rs35790011	1012	G→A	338	V→I	EU	0.051	0	0	0
NA	1438	G→A	480	V→M	EU	0	0	0.008	0
rs35395280	1490	G→C	497	C→S	EU	0.024	0	0	0
NA	1557	G→C	519	Q→H	EC	0.008	0	0	0

Abbreviations: AA, African American; AS, Asian American; EA, European American; EC, evolutionarily conserved; EU, evolutionarily unconserved; ME, Mexican American.

Note: CDS position is given in reference to the ATG start site (where position +1 is the ‘A’ in ATG). EC residues are defined as residues identical among human, mouse and rat orthologs of MATE1; all other residues were classified as EU. Population-specific allele frequencies are given.