. Author manuscript; available in PMC: 2010 Oct 4.

Published in final edited form as: Pharmacogenomics J. 2009 Jan 27;9(2):127–136. doi: 10.1038/tpj.2008.19

Table 2.

Nucleotide diversity (π) in genes encoding membrane transporters in the SLC family.

Protein	Gene Name	π_Coding (× 10⁴)	π_NS (× 10⁴)	π_S (× 10⁴)	π_NS/π_S
MATE1	SLC47A1	2.99 ± 2.80	1.53 ± 2.13	7.28 ± 8.27	0.21
OCT1	SLC22A1	7.06 ± 5.03	5.48 ± 4.61	11.9 ± 11.4	0.46
OCT2	SLC22A2	7.07 ± 5.03	2.26 ± 2.66	22.8 ± 17.6	0.10
OCT3	SLC22A3	5.43 ± 4.18	0.24 ± 0.81	21.1 ± 16.4	0.01
OCTN1	SLC22A4	8.10 ± 5.57	6.23 ± 5.03	13.9 ± 12.6	0.44

Values of π are listed as mean ± s.d., π_Coding is the nucleotide diversity in the entire coding region of each gene, π_S is the nucleotide diversity at synonymous sites and π_NS is the nucleotide diversity at nonsynonymous sites.