Table 1. Physiological variables of PND17 rats subjected to ACA and the effect of minocycline.
| Vehicle | Minocycline | |||||||
|---|---|---|---|---|---|---|---|---|
| Baseline | After return of spontaneous circulation | Baseline | After return of spontaneous circulation | |||||
| 10 mins | 30 mins | 60 mins | 10 mins | 30 mins | 60 mins | |||
| MAP | 70.0±5.0 | 70.0±5.0 | 47.3±3.9 | 48.3±2.9 | 68.3±2.9 | 69.0±5.1 | 45.7±5.3 | 46.7±2.9 |
| PaCO2 | 38.0±1.7 | 37.7±8.2 | 36.3±2.5 | 37.3±1.5 | 37.3±1.5 | 35.7±3.0 | 36.5±1.5 | 37.3±2.0 |
| PaO2 | 249±10.3 | 365.6±62.7 | 446.3±60.5 | 506.3±8.6 | 244±17.4 | 372.7±69.0 | 469±54.0 | 504.7±8.9 |
| pH | 7.35±0.02 | 7.31±0.07 | 7.40±0.08 | 7.44±0.02 | 7.34±0.02 | 7.31±0.01 | 7.47±0.02 | 7.43±0.02 |
Abbreviations: ACA, asphyxial cardiac arrest; PND, postnatal day; MAP, mean arterial blood pressure (mmHg); PaCO2, partial pressure of carbon dioxide in blood (mmHg); PaO2: partial pressure of oxygen in blood (mmHg).