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. 2009 Oct 14;30(2):299–310. doi: 10.1038/jcbfm.2009.210

Figure 3.

Figure 3

(A) Temporal changes in cerebral blood flow (CBF). Pre: before BCCAL; post: immediately after BCCAL, and at 7, 14, 21, and 28 days after BCCAL. (B) Effect of ischemic insult on learning deficit as measured by the Morris water-maze task. (C) cAMP content of white matter. (D) Photomicrographs of pCREB-stained cells in the white matter of sham (a), vehicle (b), and PDE3I (c) groups at 28 days after BCCAL. Bars=40 μm. (E) Proportion of pCREB-positive cells in the white matter. (F) Double immunofluorescent staining of pCREB (green), CNPase (red, a) and NG2 (red, b). Bars=10 μm. Values are mean±s.e.m. of 5 rats in each group. *P<0.05, **P<0.001 compared with the sham-operated group; P<0.05, P<0.001 compared with the vehicle group.