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. 2009 Oct 21;30(3):555–565. doi: 10.1038/jcbfm.2009.227

Figure 3.

Figure 3

Brief H/H challenge induced a rapid transient increase in the large-amplitude sEPSPs/sEPSCs in CA1 pyramidal cells. (A) Whole-cell current-clamp recording before, during, and 10 mins after a 2-min H/H challenge from a CA1 pyramidal neuron. H/H caused an obvious increase in large-amplitude sEPSPs. (B) Whole-cell voltage-clamp recording before, during, and 10 mins after H/H challenge from another CA1 pyramidal cell. The cell was held at −70 mV. H/H caused a significant increase in the large-amplitude sEPSCs. (C) Mean frequency of sEPSCs before and during H/H. (D) Mean amplitude of sEPSCs before and during H/H (n=8); *P<0.05.