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. 2009 Nov 18;30(4):792–800. doi: 10.1038/jcbfm.2009.242

Table 1. Mean (n=5 baboons), standard deviations of the model parameters identified in the seven ROIs and regional autoradiographic densities obtained in human braina.

Parameters Parameter estimates±standard deviations
  Frontal Ctx Parietal Ctx Thalamus Pons Caudate Putamen Cerebellum
Bmax (pmol/mL) 199±26 141±27 182±24 145±38 194±26 194±30 66±13
k1 (min−1) 0.367±0.071 0.341±0.050 0.404±0.071 0.402±0.097 0.424±0.077 0.487±0.110 0.470±0.102
k2 (min−1) 0.495±0.051 0.474±0.037 0.448±0.032 0.522±0.075 0.513±0.052 0.546±0.068 0.588±0.050
kon/VR mL/(pmol min) 0.006±0.0017 0.008±0.0027 0.005±0.0013 0.005±0.0010 0.006±0.0019 0.005±0.0015 0.006±0.0019
koff (min−1) 0.038±0.012 0.045±0.011 0.032±0.008 0.025±0.010 0.036±0.013 0.032±0.011 0.041±0.008
k5 (min−1) 0.011±0.009 0.011±0.008 0.010±0.010 0.023±0.024 0.016±0.013 0.008±0.007 0.011±0.009
k6 (min−1) 0.026±0.025 0.034±0.043 0.044±0.057 0.057±0.060 0.060±0.058 0.033±0.030 0.024±0.022
KdVR (nmol/L) 6.1±1.2 5.7±1.1 6.8±1.1 6.2±2.8 6.5±1.6 6.4±1.4 6.9±1.5
In vitro Bmax (humans) (pmol/mL)a NA NA NA 265 246 235 99

NA, not available.