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. 2010 Jan 20;30(4):703–717. doi: 10.1038/jcbfm.2010.5

Figure 2.

Figure 2

Changes in diffusion tensor imaging (DTI) in rats after transient middle cerebral artery occlusion (MCAO). Fractional anisotropy (FA) maps at different time points (D0–D14) averaged from eight animals, overlaid onto averaged apparent diffusion coefficient (ADC) maps. In the acute stages, there is a local FA increase (arrow on D0) in the ischemic territory. Subsequently, anisotropy decreases and fiber tracts degenerate ipsilateral to the lesion (arrow in D14). Corresponding ADC increases with tissue necrosis and liquefaction.