Table 1. Glucose fractional extraction and uptake during PET scanning.

	Controls	Obese rats	Controls	Diabetic rats
Fasting state
Blood [¹⁸F]FDG (AUC)	9278±1997	2369±715^*	7822±1137	1216±81^*
Brain FUR (min⁻¹)	0.063±0.009	0.135±0.020^*	0.076±0.018	0.192±0.014^*^#
Brain GU (μmol/min per 100 ml)	40±1	285±76^*	47±11	517±76^*

Glucose load
Blood [¹⁸F]FDG (AUC)	4050±847^¶	1724±235^*	2811±659^¶	1194±154^*
Brain FUR (min⁻¹)	0.098±0.004^¶	0.129±0.022	0.156±0.048^§	0.262±0.076^*
Brain GU (μmol/min per 100 ml)	211±33^¶	359±73	327±101^¶	792±225^*

AUC, area under the time–activity concentration curve (kBq × min/ml); FUR, fractional uptake rate of glucose; GU, glucose uptake rate (computed as product of FUR and glycemia).

^¶P<0.05 versus fasting state, ^§P=0.17 versus fasting state, ^*P<0.05 versus lean or both control groups, ^#P<0.05 versus obese group. The lower level of significance (P=0.17) is likely explained by higher variability of data in this subgroup, as shown by the standard error.