Table 2. Effect of TM5275 on total occlusion time in the monkey photochemically induced thrombosis model.
Treatment | N | Total occlusion time (min) |
---|---|---|
Vehicle | ||
0.5% Carboxymethyl cellulose sodium salt (per os) | 6 | 119.0±17.4 |
Clopidogrel | ||
10 mg/kg (per os) | 6 | 39.4±25.8* |
TM5275 | ||
10 mg/kg (per os) | 6 | 53.9±19.9* |
Total occlusion time was calculated during the experiment. Data are expressed as mean±s.e. *P<0.05 versus vehicle.