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Volumes of VCAM-MPIO-induced hypointensities. A 30-mins MCAO-induced binding of VCAM-MPIO in the ischemic hemisphere, whereas negligible binding was seen in IgG-MPIO-injected animals. Significantly reduced VCAM-MPIO binding was measured in preconditioned MCAO animals compared with nonpreconditioned animals. *P<0.05. Average neurologic deficit score for each group are as follows: 30 mins VCAM=2.5; 30 mins IgG=2.5; PRE 30 mins MCAO=1.2; control=0.
