Figure 4.

c-myc was prominently expressed in the tumors. c-myc was expressed in cells of the tumors at 14 day after the induced pluripotent stem (iPS) transplantation in the Sham+iPS (A) and the MCAO+PBS groups (D). c-myc expression was prominent at the interface of iPS tumor and ischemic host brain (D), as compared with sham brain (A), and c-myc stain was observed in the cylinder-like epithelial cells (B, C, E, F). (C) and (F) represent magnification of the boxed areas (c) and (f), respectively. Scale bar =2 mm (A, D), 500 μm (B, E), 100 μm (C, F). MCAO, middle cerebral artery occlusion; PBS, phosphate-buffered saline.