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Photomicrographs of 125I-MK351A binding: (A) Wistar–Kyoto (WKY) vehicle; (B) spontaneously hypertensive rat (SHR) vehicle; (C) WKY ramipril (7 days); and (D) SHR ramipril (7 days). Quantitation of binding (c.p.m./mm2) for cortical and subcortical areas in WKY and SHR strains (mean±s.d.). ***P⩽0.0001 compared with strain vehicle analysis of variance (ANOVA) using Dunnett's post hoc test.
