Table 2. Human cell numbers measured in the spleen of vaccinated HIS mice.

	Human cells (CD45+)
Groups	Total	B cells (CD19+)	T cells (CD3+)
	Absolute number (×106)	Absolute number (×106)	Absolute number (×106)
Controls (n = 10)	0.72±0.27	0.25±0.16	0.43±0.15
Vaccinated (n = 34)	3.63±0.75 **	2.03±0.46**	1.45±0.41 n.s.
Responders (n = 14)	5.63±1.54 **	3.06±0.96**	2.44±0.87 *
non-responders (n = 20)	2.06±0.45*	1.28±0.35**	0.59±0.20 n.s.

The data from the TT and HBsAg vaccination experiments are pooled. Values are expressed as a mean (± S.E.M.) number of human cells, human B cells and human T cells found in control (PBS-injected) or vaccinated animals. The vaccinated animals were further distributed between responder and non-responder animals, as determined by antigen-specific ELISA. Statistical analysis was performed on the cell numbers harvested from vaccinated animals, as compared to the control group (* p<0.05; ** p<0.01).