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Points represent a scatterplot of (A) morning and (B) evening plasminogen activator inhibitor-1 (PAI-1) (on the log scale) and apnea-hypopneas index (AHI), and lines represent the model-based unadjusted and fully adjusted piecewise linear association between morning and evening PAI-1 (on the log scale) and AHI. To ensure normal distribution assumptions of the mixed model are satisfied, PAI-1 values were log transformed before fitting the piecewise linear association.
