Table 1.

Effects of Luteolin and Gefitinib on Cell Cycle of PC-3 Cells

TREATMENT GROUP	G0/G1	S-PHASE	G2/M	APOPTOSIS
Control	60.1 ± 0.78	13.7 ± 1.01	23.2 ± 0.18	1.3 ± 0.15
Low Dose Lut	55.2 ± 0.24a	14.1 ± 0.83	26.3 ± 0.60	3.3 ± .012
Low Dose Gef	73.2 ± 0.29b	9.5 ± 1.00	14.4 ± 0.96b	1.27 ± 0.09
Low Dose Lut+Gef	56.0 ± 0.92a	16.4 ± 1.50	22.2 ± 1.17	4.1 ± 0.42
Control	61.8 ± 0.60	16.8 ± 0.80	19.1 ± 1.13	1.6 ± 0.03
High Dose Lut	45.2 ± 1.04b	15.3 ± 1.09	35.4 ± 1.10b	2.6 ± 0.31b
High Dose Gef	82.0 ± 0.13b	2.4 ± 0.07b	13.5 ± 0.03a	1.2 ± 0.15
High Dose Lut+Gef	42.1 ± 0.50b	18.2 ± 1.28	35.8 ± 1.88b	2.7 ± 0.15b

Low Dose Luteolin =17.5 µM; High Dose Luteolin =35 µM; Low Dose Gefitinib =22 µM; High Dose Gefitinib =44 µM. Significantly Different from Control (^ap<0.01 or ^bp<0.001)

^aSignificantly Different from Control (p<0.01 or

^bp<0.001)