Table 2.
Evaluating the direct model: Mean difference in log-IL-6 by categories of emotional social support
| ESS Moderate versus High B (95% CI) |
ESS Low versus High B (95% CI) |
R2 | |
|---|---|---|---|
| Entire sample | |||
| Unadjusted | 0.01 (−0.02, 0.05) | 0.13 (0.03, 0.24)* | 0.001 |
| Model 1 | 0.02 (−0.02, 0.05) | 0.09 (−0.01, 0.20) | 0.097 |
| Model 2 | 0.02 (−0.02, 0.05) | 0.06 (−0.04, 0.15) | 0.230 |
| Men | |||
| Unadjusted | 0.02 (−0.03, 0.07) | 0.15 (0.01, 0.30)* | 0.002 |
| Model 1 | 0.03 (−0.02, 0.08) | 0.10 (−0.05, 0.24) | 0.103 |
| Model 2 | 0.02 (−0.03, 0.07) | 0.05 (−0.09, 0.18) | 0.187 |
| Women | |||
| Unadjusted | −0.01 (−0.05, 0.05) | 0.11 (−0.03, 0.26) | 0.001 |
| Model 1 | 0.01 (−0.04, 0.06) | 0.07 (−0.07, 0.22) | 0.102 |
| Model 2 | 0.02 (−0.03, 0.06) | 0.06 (−0.07, 0.18) | 0.276 |
| Men, Age 45 – 64 | |||
| Unadjusted | 0.02 (−0.05, 0.08) | 0.14 (−0.05, 0.34) | 0.001 |
| Model 1 | 0.03 (−0.04, 0.10) | 0.08 (−0.12, 0.28) | 0.050 |
| Model 2 | 0.02 (−0.04, 0.09) | 0.07 (−0.12, 0.26) | 0.152 |
| Men, Age 65 – 84 | |||
| Unadjusted | 0.05 (−0.02, 0.13) | 0.17 (−0.04, 0.37) | 0.003 |
| Model 1 | 0.02 (−0.05, 0.10) | 0.12 (−0.09, 0.33) | 0.076 |
| Model 2 | 0.01 (−0.07, 0.08) | 0.03 (−0.17, 0.23) | 0.133 |
| Women, Age 45 – 64 | |||
| Unadjusted | −0.02 (−0.08, 0.05) | 0.20 (0.01, 0.39)* | 0.003 |
| Model 1 | 0.01 (−0.06, 0.06) | 0.13 (−0.06, 0.32) | 0.105 |
| Model 2 | 0.01 (−0.04, 0.07) | 0.09 (−0.07, 0.26) | 0.300 |
| Women, Age 65 – 84 | |||
| Unadjusted | 0.03 (−0.04, 0.09) | −0.01 (−0.22, 0.21) | 0.001 |
| Model 1 | 0.02 (−0.05, 0.09) | −0.02 (−0.24, 0.20) | 0.065 |
| Model 2 | 0.01 (−0.05, 0.08) | −0.02 (−0.22, 0.18) | 0.209 |
*
p<0.05
Values of IL-6 have been log-transformed.
Model 1 adjusted for age, gender, race/ethnicity, educational attainment, income, employment status, and marital status.
Model 2 adjusted for Model 1 plus smoking status, alcohol use, body mass index, hypertension, diabetes, medication use, and recent infection.