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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Mech Ageing Dev. 2010 Aug 12;131(9):562–573. doi: 10.1016/j.mad.2010.08.001

Table 1.

Distribution of recombination products obtained from spontaneous mitotic intrachromosomal recombination assay.

8AA selection (APRT−)
Events Gene Structure 2115-WRN GS21-15a +2115-luc
Gene conversion (GC) graphic file with name nihms228745t1.jpg 27/47 (58%) 118/144 (82%)
Crossover (XO) graphic file with name nihms228745t2.jpg 18/47 (38%) 26/144 (18%)
Aberrant graphic file with name nihms228745t3.jpg 2/47 (4%) 0/144 (0%)
8AA/Ganc selection (APRT−/TK−)
Events Gene Structure 2115-WRN GS21-15a +2115-luc
Crossover (XO) graphic file with name nihms228745t4.jpg 49/54 (91%) 82/105 (78%)
Crossover with GPT co- conversion (XO+GPT) graphic file with name nihms228745t5.jpg 4/54 (7%) 23/105 (22%)
Aberrant graphic file with name nihms228745t6.jpg 1/54 (2%) 0/105 (0%)
a

Recombination products for isogenic GS21-15 cell line as previously published (Sargent et al., 1997)