. Author manuscript; available in PMC: 2011 Sep 1.

Published in final edited form as: Mech Ageing Dev. 2010 Aug 12;131(9):562–573. doi: 10.1016/j.mad.2010.08.001

Table 2.

Frequencies of targeted recombination in control and WRN deficient cell lines after electroporation with the targeting vector pAG6ins0.9.

Cell line	Total No. cells electroporated	Frequency of APRT⁺ recombinants (per 10⁶) ± SEM	Frequency of GPT⁺ transfectants (per 10⁴) ± SEM	Ratio of APRT⁺:GPT⁺ (per 10³)	Clones obtained
ATS-WRN	47.6 × 10⁷	0.78 ± 0.36	4.95 ± 0.82	1.57	44
ATS-luc	40.8 × 10⁷	0.83 ± 0.14	11.4 ± 2.0	0.73	45