Table 1.
Dose (IFU/newborn mice) | No. newborn mice + cultures/total (%+) | Median (range) no. of IFU recovered from lungs |
---|---|---|
102 | 4/8 (50) | 400 (<20–4,400) |
103 | 10/12 (83) | 305 (<20–4,900,000) |
104 | 16/18 (89) | 490,000 (<20–8,800,000) |
Newborn mice born from sham-immunized-dams were inoculated at 2-PND and were euthanized at 11-PND.
Limit of detection: <20 IFU/culture.