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. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: J Infect Dis. 2010 Nov 1;202(9):1415–1423. doi: 10.1086/656534

Figure 4.

Figure 4

Stimulation of TF-dependent factor Xa generation in U937 cells. U937 cells were incubated with SubAB or its non-toxic derivative (SubAA272B) at the indicated concentrations for 1–24 h. Factor Xa generation was quantified using chromogenic substrate and A405 was read as described in the Methods. Data shown are the mean ± standard error of the mean (SEM) from triplicate assays. The differences between SubAB and SubAA272B treated cells were analyzed using Student’s t test: ***P < 0.001; **P < 0.01; *P < 0.05.