Table 2.
Risk factors for intrahepatic recurrence after initial hepatectomy
| Factor | Number of patients | Univariate P-value | Multivariate P-value |
|---|---|---|---|
| Location of CRC | 0.0733 | ||
| Colon | 27 | ||
| Rectum | 5 | ||
| Depth of CRC | 0.2112 | ||
| < ss (a1) | 19 | ||
| > se (a2) | 12 | ||
| Tumor differentiation of CRC | 0.4618 | ||
| well | 13 | ||
| moderate | 16 | ||
| poor | 1 | ||
| Lymphatic invasion of CRC | 1.0000 | ||
| Present | 25 | ||
| Absent | 5 | ||
| Venous invasion of CRC | 0.7765 | ||
| Present | 23 | ||
| Absent | 7 | ||
| Lymph node metastasis of CRC | 0.6320 | ||
| Present | 21 | ||
| Absent | 10 | ||
| Time of liver metastasis | 0.8151 | ||
| Synchronous | 12 | ||
| Metachronous | 20 | ||
| Timing of hepatectomy | 1.0000 | ||
| Synchronous | 6 | ||
| Metachronous | 26 | ||
| Number of CRCLM | 0.3516 | ||
| Single | 16 | ||
| Multiple | 16 | ||
| Size of CRCLM | 0.1218 | ||
| < 5 cm | 23 | ||
| ≥ 5 cm | 8 | ||
| Portal vein invasion of CRCLM | 0.7072 | ||
| Present | 4 | ||
| Absent | 27 | ||
| Surgical margin of CRCLM | 0.0228 | 0.0133 | |
| < 5 mm | 15 | ||
| ≥ 5 mm | 13 | ||
| Chemotherapy before hepatectomy | 0.4837 | ||
| Present | 15 | ||
| Absent | 17 | ||
| Chemotherapy after hepatectomy | 0.1976 | ||
| Present | 19 | ||
| Absent | 12 | ||
CRC: colorectal cancer, CRCLM: liver metastasis from colorectal cancer.