Table 2.
Zebrafish mutants used for the analysis of visuomotor function
| Mutant | Alleles | Phenotype | Gene | Gene product | References |
|---|---|---|---|---|---|
| lakritz | lakth241c | Absence of RGCs and complete blindness; no known developmental defect outside the retina | atoh7 (ath5) | Atonal homolog 7 | [66] |
| blumenkohl | blutc257z, blus391 | Synaptic transmission defect in retinotectal axons; enlarged tectal receptive fields; reduced visual acuity | slc17a6b (vglut2a) | Vesicular glutamate transporter 2a | [16] |
| belladonna | beltv42, bels385, belb700 | Incomplete crossing of retinal axons, reversed eye movements, 'looping' swim behavior | lhx2b | LIM-domain homeobox factor 2b | [67,93,94] |
| double indemnity | didys390, didys552 | Reversible depletion of saccadic eye movements | scn1lab | Voltage-gated sodium channel NaV1.6 | [60] |