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Cumulative survival for patients with tumors expressing estrogen receptors and progesterone receptors, stratified by HOXB13. Kaplan-Meier curves illustrating clinical outcome in terms of distant recurrence-free survival and breast cancer survival for patients with estrogen receptor (ER)-positive and progesterone receptor (PR)-positive tumors undergoing tamoxifen treatment or no endocrine therapy: (a), (b) low or no HOXB13 expression; (c), (d) moderate or high HOXB13 expression.
