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. Author manuscript; available in PMC: 2012 Jun 15.
Published in final edited form as: J Surg Res. 2009 Aug 5;168(2):197–205. doi: 10.1016/j.jss.2009.07.002

Figure 3. TRP inhibits NT- and EGF-stimulated collagen invasion by HCT116 cells in chamber-based assays.

Figure 3

Cells were treated with TRP for 6 h prior to seeding into chambers in serum-free media and then allowed to migrate overnight (A) or for 6 h (B) toward the specified chemoattractant with the indicated dose of TRP. The number of cells per high-power field (HPF) for the control condition was arbitrarily assigned a value of 1.0 and cell counts for all conditions were normalized to control conditions. (Each bar is an average of 2 or 3 wells; similar results were obtained on three separate occasions; * = p<0.05 vs. no TRP). NT, neurotensin; EGF, epidermal growth factor.