Table 2.
Model | without PC adjustment | with PC adjustment |
---|---|---|
Single-SNP tests* | 1.070 | 1.077 |
Main-effects | 1.101 | 1.059 |
Main+adj | 1.092 | 1.052 |
Haplotype | 1.064 | 1.037 |
Comparison of inflation in median test statistics () for each model with and without principal components. *Single-SNP tests without PC adjustment were Cochran-Armitage trend statistics which are not able to incorporate PC adjustment. The single-SNP statistics with PC adjustment are the 1 d.f. logistic regression.