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. 2010 Sep 9;11:80. doi: 10.1186/1471-2156-11-80

Table 2.

Inflation before and after principal component correction

Model λ^without PC adjustment λ^with PC adjustment
Single-SNP tests* 1.070 1.077
Main-effects 1.101 1.059
Main+adj 1.092 1.052
Haplotype 1.064 1.037

Comparison of inflation in median test statistics (λ^) for each model with and without principal components. *Single-SNP tests without PC adjustment were Cochran-Armitage trend statistics which are not able to incorporate PC adjustment. The single-SNP statistics with PC adjustment are the 1 d.f. logistic regression.