Table 1.
Clinical and histological characteristics of samples (QRT-PCR analysis - 50 patients)
| Variables | N (%) |
|---|---|
| Age (years) | |
| Median (range) | 67 (43-87) |
| Gender | |
| Male | 36 (72) |
| Female | 14 (28) |
| Tobacco use | |
| Yes | 38 (76) |
| No | 12 (24) |
| Alcohol use | |
| Yes | 34 (68) |
| No | 16 (32) |
| Tumor Site | |
| Tongue | 33 (66) |
| Floor of mouth | 10 (20) |
| Alveolar | 4 (8) |
| Buccal mucosa | 2 (4) |
| Retromolar | 1 (2) |
| T category | |
| T1-T2 | 16 (32) |
| T3-T4 | 34 (68) |
| Nodal status (pathological) | |
| Negative (N0) | 28 (56) |
| Positive (N1, N2b, N2c) | 22 (44) |
| Tumor Stage | |
| I-II | 14 (28) |
| III-IV | 36 (72) |
| Tumor Grade | |
| Well differentiated | 4 (8) |
| Moderately differentiated | 41 (82) |
| Poorly differentiated | 5 (10) |
| Tumor thickness (mm) | |
| Median (range) | 12 (2-31) |
| Perineural invasion | |
| Yes | 20 (40) |
| No | 30 (60) |
| Angiolymphatic invasion | |
| Yes | 16 (32) |
| No | 34 (68) |
| Recurrence | |
| Yes | 23 (46) |
| No | 27 (54) |
| Outcome* | |
| Alive, no evidence of disease | 25 (50) |
| Alive with disease | 6 (12) |
| Dead of disease | 15 (30) |
| Dead of other causes | 4 (8) |
* last date of follow-up: October, 2009.