Table 4.

Expression of Gene Biomarkers in North American and Malaysian Samples

Symbol	Parameter	ANXA3	CLEC4D	LMNB1	PRRG4	TNFAIP6	VNN1
North	Fold Change	1.71	1.50	1.37	1.72	1.58	1.53
American	p-Value	< 0.0001	< 0.0001	< 0.0001	< 0.0001	< 0.0001	< 0.0001
Malaysian	Fold Change	2.06	1.75	1.65	1.37	1.80	1.87
	p-Value	< 0.0001	< 0.0001	< 0.0001	< 0.0003	< 0.0001	< 0.0001

Note: North American Training Set comprises 112 CRC and 120 control samples.

Malaysian Study Set comprises 99 CRC and 111 control samples.

The significance of the fold changes were evaluated using Mann-Whitney independent sample rank sum tests.