Table 4.
HBV DNA Status in HBsAg positive subjects by demographic and HIV status
| AIDS (pretreatment time point) (N = 29) | non-AIDS (N = 41) * | Total (N = 66) | ||||
|---|---|---|---|---|---|---|
| HBV DNA | Detection | Geometric | Detection | Geometric | Detection | Geometric |
| N (%) | Mean (c mL-1) | N (%) | Mean (c mL-1) | N (%) | Mean(c mL-1) | |
| Sex: | ||||||
| Female | 7 (43.7)* | 2.3 × 102 | 7 (26.9) | 6.2 × 103 | 14 (29.2) | 1.2 × 104 |
| P-value difference | 0.05 | 0.04 | 0.07 | 0.07 | 0.20 | 0.64 |
| Age | ||||||
| 0-9 years | 1 (100.0) | 27.2 | -- | -- | 1 (100.0) | 2.7 × 101 |
| 10-24 years | 1 (100.0) | 6.7 × 102 | 4 (28.5) | 1.1 × 104 | 5 (29.4) | 6.3 × 103 |
| 25-34 years | 5 (50.0) | 2.9 × 102 | 1 (7.1) | 6.6 × 103 | 6 (21.3) | 4.9 × 102 |
| 35-44 years | 9 (69.2) | 1.9 × 102 | 0 (0.0) | -- | 9 (52.9) | 1.9 × 102 |
| 45-93 years | 2 (50.0) | 2.2 × 103 | 2 (33.3) | 1.9 × 103 | 4 (40.0) | 2.0 × 103 |
| P-value difference | 0.83 | 0.81 | 0.31 | 0.30 | 0.12 | 0.53 |
| HIV Status | ||||||
| HIV-1 | 14 (58.3) | 2.2 × 102 | 3 (21.4) | 1.1 × 104 | 17 (40.4)* | 4.3 × 102 |
| HIV-2 | 2 (66.2) | 1.3 × 103 | 3 (14.2) | 2.9 × 103 | 5 (18.5)* | 2.1 × 103 |
| Dual Infection | 2 (100.0) | 2.4 × 102 | 1 (50.0) | 1.2 × 104 | 3 (75.0)* | 8.7 × 102 |
| P-value difference | 0.77 | 0.48 | 0.37 | 0.34 | 0.003 | 0.09 |
| CD4 Count | ||||||
| < 200 cells μL-1** | 11 (73.3) | 2.6 × 102 | -- | -- | -- | -- |
| > 200 cells μL-1 | 5 (34.4) | 1.8 × 102 | -- | -- | -- | -- |
| P-value difference | 0.22 | 0.19 | -- | -- | -- | -- |
| Total | 18 (62.0) | 2.6 × 102 | 7 (16.6) | 6.2 × 103 | 25 (34.2) | 6.5 × 102 |
*18 (62%) out of 29 AIDS patients and 7 (16.6%) out of 42 non-AIDS HBsAg individuals tested positive for HBV DNA.
** Number and percent are reported for CD4 count <200.