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Temporal evolution of apparent diffusion coefficient (ADC) (A) and cerebral blood flow (CBF) (B) in the core and mismatch regions defined before treatment (45 mins) in permanently occluded rats. Dimethyl sulfoxide (DMSO) or saline was administered 1 h after occlusion. Dimethyl sulfoxide group: core=open triangle, mismatch=open circles. Saline group: core=closed triangles, mismatch=closed circles. *P<0.05; **P<0.01; ***P<0.001.
