Table 1.
Physiologic data before occlusion (baseline) and 3 or 4 h after MCAO
| Experiment 1 |
Experiment 2 |
|||||||
|---|---|---|---|---|---|---|---|---|
| DMSO−20 | Saline−20 | DMSO+1 | Saline+1 | DMSO+2 | Saline+2 | DMSO+1 | Saline+1 | |
| Baseline | ||||||||
| MABP | 95±7 | 89±12 | 88±10 | 96±9 | 94±7 | 90±11 | 89±10 | 92±13 |
| Temp | 36.8±0.3 | 36.7±0.03 | 36.6±0.04 | 36.9±0.02 | 37.0±0.03 | 36.7±0.03 | 36.6±0.04 | 36.7±0.04 |
| pO2 | 84±9 | 91±10 | 88±9 | 85±5 | 86±7 | 90±8 | 87±8 | 89±6 |
| pCO2 | 42±6 | 41±8 | 42±5 | 39±6 | 43±6 | 41±5 | 38±6 | 42±5 |
| pH | 7.43±0.04 | 7.4±0.03 | 7.41±0.03 | 7.42±0.04 | 7.4±0.05 | 7.42±0.03 | 7.38±0.04 | 7.41±0.03 |
| Gluc | 169±31 | 180±34 | 153±28 | 167±37 | 187±35 | 161±37 | 175±28 | 159±38 |
| 3 or 4 h | ||||||||
| MABP | 93±11 | 91±12 | 93±8 | 97±11 | 98±12 | 93±7 | 95±10 | 90±10 |
| Temp | 36.9±0.02 | 36.8±0.03 | 36.8±0.04 | 37.2±0.03 | 37.1±0.03 | 36.8±0.03 | 36.9±0.03 | 37.1±0.04 |
| pO2 | 87±8 | 86±7 | 92±9 | 86±8 | 86±6 | 93±9 | 85±9 | 86±6 |
| pCO2 | 39±5 | 36±8 | 40±5 | 43±6 | 37±6 | 38±6 | 36±5 | 37±6 |
| pH | 7.39±0.05 | 7.41±0.03 | 7.42±0.03 | 7.38±0.04 | 7.37±0.05 | 7.41±0.04 | 7.37±0.03 | 7.38±0.05 |
| Gluc | 147±28 | 164±21 | 141±30 | 136±33 | 159±27 | 151±31 | 147±31 | 138±33 |
DMSO=dimethyl sulfoxide; MABP=mean arterial blood pressure (mm Hg); Temp=rectal body temperature (°C); pO2 and pCO2 in mm Hg; Gluc=plasma glucose (mg/dL). In experiments 1 and 2, physiologic data were acquired at 3 and 4 h after MCAO, respectively.