Table 1.
Physical properties of conventional liposomes and DCL.
| Liposomes (Lipid composition) | Lipid weight ratio |
Liposome size (nm)a) |
DOX loading efficiency (%)b) |
DOX amount of DCL (mg/ml) |
|---|---|---|---|---|
| Conventional liposomes (HSPC:CHOL) | 3:1 | 128.1±0.1 | 94 | – |
| DCL (HSPC:CHOL:DSPE-PEG2000-DOX) | 3:1:1 | 128.9±1.3 | 75 | 0.049 |
Measured by light scattering.
Calculated according to Equation (1).