Table 2.
Mortality Rates.
| Variable | Early Antiretroviral Therapy (N = 252) |
Deferred Antiretroviral Therapy (N = 125) |
Total (N = 377) |
Hazard Ratio (95% CI)* |
P Value |
|---|---|---|---|---|---|
| Deaths — no. (%) | 10 (4) | 20 (16) | 30 (8) | 0.24 (0.11–0.51) | <0.001 |
| Person-years of follow-up — no. | 205 | 94 | 299 | ||
| Overall death rate per 100 person-years — % (95% CI) | 4.9 (2.3–9.0) | 21.2 (13.0–32.7) | 10.0 (6.8–14.3) | ||
| Rate of death during follow-up — % (95% CI) | |||||
| 0–13 wk | 9.8 (3.6–21.4) | 40.6 (21.0–71.0) | |||
| >13–26 wk | 3.7 (0.4–13.2) | 19.7 (6.4–45.9) | |||
| >26–52 wk | 3.1 (0.4–11.2) | 6.8 (0.8–24.7) |
Hazard ratios for death are for the comparison of the early-therapy groups with the deferred-treatment group.