FIG. 6.

Splenocyte CD4⁺CD25⁺FoxP3⁺ (T_reg) cells are increased in lipopolysaccharide (LPS)-pretreated mice, but not in synthetic triterpenoid, CDDO-Me-pretreated mice. Whole individual spleens (n = 1 spleen per group) from each of the indicated pretreatment groups were used to measure T_reg cells. Indicated percentages are percentages of total cells as determined by analytical software. Relevant isotype controls were used to set the illustrated region gates (data not shown). Axes to histograms for each row are indicated to the left of the histograms. Representative results are from 1 of 3 independent experiments.