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(A) Oncostatin M (OSM) and OSM receptor protein expression is up-regulated by unilateral ureteral obstruction (UUO). Expression of OSM and OSM receptor in UUO rat kidneys and in normal control kidneys at 6 and 24 h after obstruction by Western blot analysis. (B) Real-time PCR analysis of α-SMA and collagen I EMT markers following UUO in rats. No difference in α-SMA and Col I mRNA levels is observed in the first 24 h following UUO.
