Figure 4. siRNA hits enhance apoptosis in the presence of EGFR inhibitor.
Apoptosis was determined by annexin-V labeling and normalized to negative control siRNA. Composite results from two independent experiments are shown as odds ratio columns; black, DMSO-treated; white, erlotinib-treated. Asterisks indicate statistically significant (FDR ≤ 0.05) erlotinib-gene interactions from two independent experiments.