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. Author manuscript; available in PMC: 2010 Oct 5.
Published in final edited form as: Alcohol Clin Exp Res. 2009 Apr 9;33(7):1220–1230. doi: 10.1111/j.1530-0277.2009.00946.x

Fig. 8.

Fig. 8

Our current model for the mechanism by which iNOS inhibitors reduce EtOH-induced steatohepatitis. They do so by preventing oxidative stress-induced increases in intestinal hyperpermeability and the endotoxemia that would otherwise result.