TABLE I.
Baseline Risk Factor Levels (Mean (SEM) or Percent) by Quartile of D-Dimer, MESA, 2000–2002
| D-dimer Quartiles | ||||
|---|---|---|---|---|
| Baseline Factor | ≤0.13 µg/mL | 0.14 – 0.20 µg/mL | 0.21 – 0.37 µg/mL | >0.37 µg/mL |
| Unadjusted Covariates | ||||
| N | 1839 | 1559 | 1623 | 1370 |
| Age (years) | 55.6 (0.20) | 61.0 (0.26) | 63.9 (0.25) | 67.1 (0.26) |
| Male | 55.7% | 46.3% | 42.5% | 42.7% |
| Race/Ethnicity | ||||
| White | 40.9% | 42.0% | 37.4% | 32.2% |
| Chinese American | 16.8% | 11.6% | 10.7% | 8.1% |
| African American | 21.6% | 25.8% | 30.1% | 34.6% |
| Hispanic | 20.7% | 20.6% | 21.8% | 25.1% |
| Covariates adjusted for age, sex and race | ||||
| Body mass index (kg/m2) | 27.2 (0.12) | 28.4 (0.14) | 28.6 (0.13) | 29.2 (0.13) |
| Current Smoker | 11.0% | 13.5% | 13.3% | 13.6% |
| Ex-Smoker | 36.9% | 38.1% | 56.3% | 33.7% |
| Pack-years (total sample) | 9.9 (0.53) | 11.6 (0.59) | 12.0 (0.54) | 12.6 (0.57) |
| Alcohol intake (drinks/week) | 4.2 (0.20) | 3.4 (0.22) | 4.2 (0.20) | 3.9 (0.21) |
| Systolic Blood Pressure (mmHg) | 125.9 (0.48) | 126.5 (0.54) | 126.2 (0.49) | 127.9 (0.52) |
| Any Anti-hypertensive use | 31.7% | 34.8% | 33.2% | 39.4% |
| LDL Cholesterol (mg/dl) | 115.5 (0.77) | 118.5 (0.85) | 118.2 (0.78) | 117.3 (0.83) |
| HDL Cholesterol (mg/dl) | 53.2 (0.33) | 50.3 (0.36) | 50.4 (0.33) | 49.6 (0.35) |
| Statin use | 16.1% | 15.8% | 14.3% | 13.3% |
| Exercise (MET-h/week) | 25.6 (0.94) | 26.5 (1.04) | 27.1 (0.96) | 24.3 (1.01) |
| Impaired Fasting | ||||
| Glucose | 27.5% | 29.3% | 27.4% | 27.8% |
| Diabetes | 13.1% | 14.3% | 14.8% | 14.0% |
| Fibrinogen (mg/dL) | 325 (1.7) | 342 (1.9) | 352 (1.7) | 369(1.8) |
| Interleukin-6 (pg/mL) | 1.3 (0.03) | 1.5 (0.03) | 1.6 (0.03) | 1.9 (0.03) |
| C-Reactive Protein (mg/L) | 2.6 (0.14) | 3.3 (0.15) | 4.1 (0.14) | 5.0 (0.15) |