Table 3.

Estimated Hazard Ratios (95% Confidence Interval) from Cox Proportional Hazard Models Assessing Parental Longevity (OPEL vs OPUS) as a Predictor of Dementia.

Outcome	Model 1*	Model 2†	Model 3‡	Model 4§	Model 5
All dementia	0.64 (0.43–0.97)	0.68 (0.45–1.02)	0.70 (0.46–1.05)	0.69 (0.46–1.04)	0.70 (0.47–1.06)
Alzheimer’s Dementia	0.57 (0.35–0.93)	0.60 (0.37–0.99)	0.61 (0.37–0.99)	0.59 (0.36–0.97)	0.62 (0.36–1.07)

^*Model 1: OPEL versus OPUS using age as the time scale.

^†Model 2: Model 1 + (gender, education, race/ethnicity).

^‡Model 3: Model 2 + (hypertension, myocardial infarction, diabetes mellitus, stroke).

^§Model 4: Model 2 + vascular index (sum of conditions present: hypertension, myocardial infarction, diabetes mellitus, stroke).

Model 5: Model 2+ vascular index + ever smoking + dyslipidemia.