Table II.
Genes with increased expression in IL-2Rα-deficient (KO) P14 8 days post-infection with LCMV.
| Name | fold up (KO) | function |
|---|---|---|
| Bcl6 | 1.9 | memory diff. |
| IL-2 | 2.3 | cytokine |
| TNFα | 1.5 | cytokine |
| IL-10 | 1.9 | cytokine |
| IL-17F | 1.7 | cytokine |
| CXCR5 | 5.4 | SLO trafficking |
| CCR7 | 3.3 | SLO trafficking |
| CTLA4 | 1.5 | neg. costimulation |
| CD40 | 2.7 | costimulation |
| CD44 | 1.6 | activation marker |
| TCF-1 | 2.2 | CTL diff. arrest |
| LEF-1 | 1.3 | CTL diff. arrest |
All fold differences are significant (p<.05, n=4).