Table 1. Characteristics of pregnant or postpartum women with 2009 A/H1N1v influenza infection.
ICU patients (severe) (n = 40) | Hospitalized non-severe patients (moderate) (n = 111) | Outpatients (mild) (n = 164) | p value | |
Age, years | ||||
<20 | 5 (13) | 3 (3) | 2 (1) | |
20–34 | 28 (70) | 89 (80) | 131 (80) | 0.001 |
≥35 | 7 (18) | 19 (17) | 31 (19) | |
Median age [min-max] | 28 [17–45] | 28 [15–43] | 28 [14–45] | NS |
Pregnancy trimester | ||||
1st trimester | 3 (8) | 0 (0) | 33 (20) | |
2nd trimester | 9 (23) | 24 (22) | 76 (46) | <0.001 |
3rd trimester and postpartum | 28 (70) | 87 (78) | 55 (34) | |
Chronic pre-existing disease | 23 (58) | 32 (29) | 44 (27) | <0.001 |
Obesity (BMI>30) | 6 | 17 | 16 | NS |
Respiratory disease * | 11 | 11 | 9 | <0.001 |
Cardiac or vascular disease | 3 | 1 | 5 | NS |
Metabolic disease other than diabetes** | 1 | 2 | 6 | NS |
Diabetes except gestational diabetes | 1 | 1 | 2 | NS |
Neurologic disease | 1 | 2 | 5 | NS |
Renal disease | 0 | 0 | 2 | NS |
Hepatic disease | 1 | 0 | 1 | NS |
Hematologic disease | 2 | 1 | 3 | NS |
Immunosuppression | 1 | 1 | 1 | NS |
Pregnancy-related disorders | 3 (8) | 12 (11) | 11 (7) | NS |
Gestational diabetes | 1 | 10 | 9 | NS |
Preeclampsia | 1 | 0 | 2 | NS |
Others | 2 | 2 | 0 | NS |
Chronic medication (pre- or intra-pregnancy) | 13 (33) | 11 (10) | 18 (11) | <0.001 |
Corticosteroids | 0 | 2 | 1 | NS |
Immunosuppression | 0 | 0 | 1 | NS |
Others *** | 13 | 9 | 17 | <0.001 |
Values: N (%) unless stated otherwise. NS: non-significant.
*includes asthma, restrictive syndrome.
**includes thyroid and adrenal insufficiency.
***includes bronchodilators, insulin, salicylic acid, fractionated heparin, L-thyroxin, antihypertensive agents.