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. 2010 Oct 5;5(10):e13112. doi: 10.1371/journal.pone.0013112

Table 2. Influenza symptoms, clinical course, and treatments of pregnant or postpartum women with 2009 A/H1N1v influenza.

ICU patients (severe) (n = 40) Hospitalized non severe patients (moderate) (n = 111) Outpatients (mild) (n = 164) p value
Symptoms *
Hyperthermia >37.8°C 34 (85) 97 (89) 131 (85) NS
Cough 28 (70) 93 (85) 134 (86) 0.04
Muscle aches 14 (35) 56 (51) 94 (61) 0.01
Headache 5 (13) 44 (40) 61 (39) 0.004
Rhinorrhea 3 (8) 34 (31) 51 (33) 0.006
Sore throat 2 (5) 14 (13) 19 (12) NS
Shortness of breath 31 (78) 22 (20) 14 (9) <0.001
Vomiting 6 (15) 14 (13) 10 (6) NS
Diarrhea 1 (3) 1 (1) 3 (2) NS
Antiviral treatment 40 (100) 109 (98) 150 (91) 0.01
≤2 days 18 (45) 87 (80) 132 (88)
3-5 days 10 (25) 16 (15) 13 (9) <0.001
>5 days 12 (30) 6 (6) 5 (3)
Initial antibiotic therapy 32 (80) 75 (68) 65 (40) <0.001
Hospitalization ward
Obstetric ward NA 94 (85) NA -
Medical ward NA 17 (15) NA -
Specific obstetric care * , ** 23/39 (59) 11/109 (10) 0/155 (0) <0.001
Corticosteroids (fetal pulmonary maturation) 10 (26) 4 (4) 0 (0) <0.001
Tocolysis 0 (0) 8 (7) 0 (0) 0.005
Artificial induction of labor 1 (3) 1 (1) 0 (0) NS
Cesarean section 17 (44) 1 (1) 0 (0) <0.001
Fetal consequences * , ** 14/39 (36) 4/109 (4) 0/155 (0) <0.001
Prematurity (<37 weeks of gestation) 13 (33) 2 (2) 0 (0) <0.001
Miscarriage 0 (0) 1 (1) 0 (0) NS
Stillbirth 1 (3) 1 (1) 0 (0) NS

Values: N (%). NA: not applicable, NS: non-significant.

*Some data were only available for 109 non-severe hospitalized patients and 155 outpatients on March 31st, 2010.

**Information about obstetric care or fetal consequences is directly related to H1N1 illness. Obstetric care and fetal consequences were registered for only the 39 ICU-hospitalized women with a prepartum onset of influenza symptoms and excluding the only post-partum case in the registry.