Table 1. Summary of samples analyzed in this study.
Country of origin | Matrix | Number/description | Clinical pathology | Nodulectomy results | Average mf per mg |
Cameroon | Plasma | 16 O. volvulus infected | Palpable nodule(s) | All nodules contained live worms | —a |
18 uninfected controls | — | NA | 0b | ||
1 calcified worm | Palpable nodule(s) | 1 dead, calcified worm | — | ||
2 ambiguous lipoma | Palpable nodule(s) | Fat deposit | — | ||
1 indeterminant infection status | — | — | — | ||
Ghana | Serum | 15 O. volvulus infected | Palpable nodule(s) | — | 12c |
10 O.volvulus, mf+ | Acute papular onchodermatitis | — | +d | ||
Liberia | Serum | 10 O. volvulus infected | — | — | 527e |
Guatemala | Serum | 21 O. volvulus infected | Palpable nodule(s) | 24% of nodules sampled all worms dead | — |
17 uninfected controls | — | NA | — | ||
6 Leishmania braziliensis | — | NA | — | ||
6 Leishmania mexicana | — | NA | — | ||
5 Trypanosoma cruzi | — | NA | — | ||
India | Plasma | 4 Wuchereria bancrofti | — | NA | — |
USA | Plasma | 3 O.volvulus uninfected, no known disease | — | NA | — |
Serum | 3 O. volvulus uninfected, no known disease | — | NA | — |
— indicates no measurement made.
no mf were measured in samples collected from four different anatomical locations from the 18 control individuals included in this analysis.
Samples are known to be mf+, but records are not available.
Average number of mf collected from six different anatomical locations from the 10 patients included in this analysis.