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. 2010 Oct 6;102(19):1478–1488. doi: 10.1093/jnci/djq356

Table 2.

Number and proportion of women who developed atypia or worse (by cytology) or cervical intraepithelial neoplasia grade 2 (CIN2) or worse (by histology) during the entire follow-up period of 13.4 years in relation to human papillomavirus (HPV) type detected at baseline among cytologically normal Danish women

HPV species and type Proportion developing atypia or worse during follow-up
Proportion developing CIN2 or worse during follow-up
All women with the given HPV type Women with the given HPV type alone Women with the given HPV type plus other high-risk HPV types except HPV16 Women with the given HPV type plus HPV16 with or without other high-risk HPV types All women with the given HPV type Women with the given HPV type alone Women with the given HPV type plus other high-risk HPV types except HPV16 Women with the given HPV type plus HPV16 with or without other high-risk HPV types
N (%) % % % N (%) % % %
Alpha 9
    HPV16 113 (38.2) 40.7 36.4 NA 82 (27.7) 28.5 27.2 NA
    HPV31 77 (30.8) 29.4 27.6 42.6 49 (19.6) 15.7 17.1 31.9
    HPV33 7 (34.8) 31.9 31.4 48.4 36 (22.0) 19.1 16.3 41.9
    HPV35 17 (35.4) 27.3 40.6 20.0 11 (22.9) 18.2 28.1 0
    HPV52 73 (29.7) 20.3 30.9 39.1 39 (15.9) 4.7 19.9 19.6
    HPV58 24 (27.0) 16.7 29.4 22.2 18 (20.2) 16.7 22.1 11.1
Alpha 7
    HPV18 38 (32.8) 23.1 37.7 28.6 24 (20.7) 15.4 23.2 19.0
    HPV39 30 (21.7) 14.3 22.5 28.6 16 (11.6) 3.6 10.1 28.6
    HPV45 26 (19.3) 14.9 21.3 23.1 15 (11.1) 8.5 10.7 23.1
    HPV59 11 (17.5) 4.2 19.4 50.0 6 (9.5) 0 6.5 50.0
    HPV68 16 (13.7) 3.8 15.6 21.4 8 (6.8) 0 7.8 14.3
Alpha 6
    HPV53 21 (19.3) 0 17.1 38.1 12 (11.0) 0 7.9 28.6
    HPV56 22 (18.0) 19.4 13.8 28.6 9 (7.4) 2.8 9.2 9.5
    HPV66 27 (22.3) 16.7 17.2 21.8 18 (14.9) 0 12.6 25.0
Alpha 5
    HPV51 27 (19.3) 17.2 16.7 29.4 18 (10.2) 8.6 6.0 23.5

*NA = not applicable.