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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Mol Biochem Parasitol. 2010 Jul 30;174(2):150–153. doi: 10.1016/j.molbiopara.2010.07.006

Table 1.

Activities of three mitochondrial ubiquinone oxidoreductases

substrate inhibitor specific activitya
nmol/min/mg prot
DHOb 13.8
DHO (50 µl DMSO) 12.1
DHO 5FOc, 0.5 mM (DMSO) 5.71
malate 11.1
succinate 9.73
succinate malonate, 10 mM 5.79
a

acceptor cosubstrate = 100 µM QD + 60 µM 2,6-dichloroindophenol

b

DHO = L-dihydroorotate

c

5FO = 5-fluoroorotate