Table 1.
Activities of three mitochondrial ubiquinone oxidoreductases
substrate | inhibitor | specific activitya nmol/min/mg prot |
---|---|---|
DHOb | 13.8 | |
DHO | (50 µl DMSO) | 12.1 |
DHO | 5FOc, 0.5 mM (DMSO) | 5.71 |
malate | 11.1 | |
succinate | 9.73 | |
succinate | malonate, 10 mM | 5.79 |
acceptor cosubstrate = 100 µM QD + 60 µM 2,6-dichloroindophenol
DHO = L-dihydroorotate
5FO = 5-fluoroorotate